Chemical Name: 2-Methyl-5-Nitroimidiazole-1-Ethanol
Trade Names: METRONIDAZOL
General Applications:
Metronidazole is used to treat parasitic infections including Giardia infections of the small
intestine, amebic liver abscess and amebic dysentery (infection of the colon causing bloody
diarrhea), bacterial vaginosis, trichomonas vaginal infections, and carriers of trichomonas (both
sexual partners) who do not have symptoms of infection. Metronidazole is also used alone or in
combination with other antibiotics in treating abscesses in the liver, pelvis, abdomen and brain
caused by susceptible anaerobic bacteria.
Introduction:
Metronidazole is a nitroimidazole anti-infective medication used mainly in the treatment of
infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa.
| TEST |
STANDARD |
Unit |
Ref |
| IR spectra |
Spectrum obtained with standard Metronidazole |
– |
USP41-NF36 |
| Organic Impurities |
—Tinidazole Compound A NMT 0.1
— Any single unspecified Impurity NMT 0.1
—Total Impurities NMT 0.2
|
%wt |
USP41-NF36 |
| Loss on drying |
Max 0.5 |
%wt |
USP41-NF36 |
| Residue on Ignition |
Max 0.1 |
%wt |
USP41-NF36 |
| Assay |
99 – 101 |
%wt |
USP41-NF36 |
| Heavy metals |
Max 50 |
ppm |
USP41-NF36 |
| Residual solvents |
Defined as Organic volatile chemicals |
ppm |
USP41-NF36 |
|
Packaging Type
|
Net weight
|
Gross weight
|
No. of drums per pallet
|
No. of pallets in a 20 FLC
|
Shelf life
|
IMCO Class
|
|
PE bags in Paper Drums
|
25 Kgs
|
40 Kgs
|
6
|
20
|
2 yrs
|
Non-Imco
|
Safety, Handling & Storage:
Full information on the safety, handling and storage of KECASs is available in the corresponding Material Safety Data Sheet (MSDS).